Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 10/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15178306 | 0.81 | TAS1R3 (0.37) | RIPK1 | |
| SCHEMBL15178107 | 0.77 | TRPA1 (0.41) | — | |
| SCHEMBL14402452 | 0.77 | DPP4 (0.44) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL15178217 | 0.76 | RIPK1 (0.35) | DPP4DPP7DPP8RIPK1 | |
| SCHEMBL14402426 | 0.76 | DPP4 (0.43) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL13849908 | 0.76 | DPP4 (0.43) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL15178227 | 0.75 | RIPK1 (0.37) | DPP4RIPK1 | |
| SCHEMBL15178322 | 0.73 | NR3C1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8281694 | 0.73 | DPP4 (0.48) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL8282066 | 0.73 | DPP4 (0.48) | DPP4DPP7DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847533-B1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2013-08-14 | — | — | EP | disclosed |