Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146656 | 0.81 | HSD17B10 (0.47) | HSD17B10GAACYP2C19BRD4POLB | |
| SCHEMBL30747873 | 0.81 | HSD17B10 (0.47) | HSD17B10GAACYP2C19BRD4POLB | |
| Butane SCHEMBL1395551 | 0.81 | KDM4E (0.47) | HSD17B10POLBL3MBTL1TDP1MEN1 | |
| SCHEMBL150146 | 0.80 | THRB (0.52) | HSD17B10GAAFABP4THRBTDP1 | |
| SCHEMBL8129651 | 0.79 | AKR1C3 (0.45) | HSD17B10GAAFABP4MEN1KMT2A | |
| Butane SCHEMBL1960365 | 0.76 | KDM4E (0.44) | HSD17B10POLBL3MBTL1TDP1MEN1 | |
| SCHEMBL10721263 | 0.75 | AKR1C3 (0.57) | GAAFABP4L3MBTL1ATMMEN1 | |
| SCHEMBL1022424 | 0.75 | CHRM2 (0.58) | HSD17B10GAAPOLBL3MBTL1TDP1 | |
| SCHEMBL30994802 | 0.75 | CHRM2 (0.58) | HSD17B10GAAPOLBL3MBTL1TDP1 | |
| SCHEMBL12691945 | 0.74 | TSHR (0.53) | GAAPOLBL3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120614-A2 | HOMOGENEOUS ERYTHROPOIETIN AND OTHER PEPTIDES AND PROTEINS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2007-10-25 | — | — | WO | disclosed |