Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.88 |
| ▸ | CTSL | P07711 | 4/20 | 0.83 |
| ▸ | CTSS | P25774 | 4/20 | 0.83 |
| ▸ | CTSB | P07858 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14404063 | 0.93 | CTSK (0.88) | CTSKCTSLCTSSCTSB | |
| SCHEMBL14260179 | 0.91 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5637331 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6646961 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5636049 | 0.88 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5638936 | 0.88 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5638946 | 0.88 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL14260273 | 0.85 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL14260280 | 0.85 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6489737 | 0.83 | CTSK (1.00) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282512-B2 | Cycloalkyl ketoamides derivatives useful as cathepsin K inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-16 | — | — | US | disclosed |