SCHEMBL14404266

SCHEMBL14404266

NCc1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(CI)cn2)cc1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.61
KLK1 P06870 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14404267 0.89 F10 (0.72) F10
SCHEMBL12134451 0.87 F10 (0.65) F10
SCHEMBL10179144 0.87 F10 (0.80) F10
SCHEMBL14404592 0.85 F10 (0.55) F10
SCHEMBL14381018 0.84 F10 (0.62) F10KLK1
SCHEMBL14599849 0.84 F10 (0.77) F10
SCHEMBL14404591 0.83 F10 (0.76) F10
SCHEMBL14404615 0.82 F10 (0.75) F10
SCHEMBL14629731 0.81 F10 (0.75) F10
SCHEMBL14404606 0.80 F10 (0.56) F10KLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7285565-B2 Benzamides and related inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-10-23 US disclosed