Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14404269 | 0.90 | F10 (0.51) | F10KCNH2KLKB1 | |
| SCHEMBL14404271 | 0.89 | F10 (0.49) | F10KCNH2 | |
| SCHEMBL14404275 | 0.89 | F10 (0.58) | F10KCNH2 | |
| SCHEMBL14404267 | 0.88 | F10 (0.72) | F10 | |
| SCHEMBL14629808 | 0.85 | F10 (0.46) | F10KCNH2KLK1KLK5KLKB1 | |
| SCHEMBL10146294 | 0.85 | F10 (0.77) | F10KCNH2 | |
| SCHEMBL14310022 | 0.85 | NPC1 (0.61) | F10KCNH2KLK1KLK5 | |
| SCHEMBL10146365 | 0.85 | F10 (0.59) | F10KCNH2KLK1KLK5 | |
| SCHEMBL13349198 | 0.85 | F10 (0.59) | F10KCNH2KLK1KLK5 | |
| SCHEMBL14629783 | 0.85 | F10 (0.61) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285565-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-10-23 | — | — | US | disclosed |