Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14404489 | 0.90 | F10 (0.52) | F10KCNH2 | |
| SCHEMBL14404606 | 0.89 | F10 (0.56) | F10KCNH2 | |
| SCHEMBL14404592 | 0.89 | F10 (0.55) | F10 | |
| SCHEMBL12134453 | 0.87 | NPC1 (0.60) | F10KCNH2KDM4ENPC1ALDH1A1 | |
| SCHEMBL14629802 | 0.86 | F10 (0.47) | F10KCNH2NPC1RAB9A | |
| SCHEMBL10181291 | 0.86 | F10 (0.51) | F10KCNH2KDM4ENPC1ALDH1A1 | |
| SCHEMBL10146425 | 0.86 | KMT2A (0.53) | F10KCNH2KDM4ENPC1ALDH1A1 | |
| SCHEMBL10146320 | 0.86 | F10 (0.65) | F10KCNH2SMN1; SMN2 | |
| SCHEMBL14404273 | 0.84 | F10 (0.62) | F10KCNH2 | |
| SCHEMBL14404275 | 0.84 | F10 (0.58) | F10KCNH2KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285565-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-10-23 | — | — | US | disclosed |