Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694281 | 0.82 | MEN1 (0.62) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL18934335 | 0.81 | MEN1 (0.68) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL8886284 | 0.77 | MEN1 (0.77) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL28738835 | 0.77 | MEN1 (1.00) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL17624931 | 0.77 | DAO (0.57) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL31743953 | 0.77 | MEN1 (0.77) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL5718587 | 0.74 | MEN1 (0.68) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL24270831 | 0.73 | MEN1 (0.58) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL30578495 | 0.73 | MEN1 (0.58) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL4934267 | 0.72 | ATM (0.54) | MEN1KMT2ALMNAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023812-A1 | MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 (MPGES1) INHIBITORS | NOVASAID AB (SE) | 2011-03-03 | — | — | WO | disclosed |
| WO-2011023812-A1 | MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 (MPGES1) INHIBITORS | NOVASAID AB (SE) | 2011-03-03 | — | — | WO | disclosed |