SCHEMBL31743953

SCHEMBL31743953

O=c1[nH]c2ccc(Cl)cc2n1-c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.77
KMT2A Q03164 2/20 0.77
LMNA P02545 1/20 0.77
L3MBTL1 Q9Y468 1/20 0.77
AURKA O14965 1/20 0.60
DAO P14920 1/20 0.57
KDM4E B2RXH2 2/20 0.52
GAA P10253 1/20 0.52
ADORA3 P0DMS8 2/20 0.51
GABRP O00591 1/20 0.51
GABRD O14764 1/20 0.51
GABRA1 P14867 1/20 0.51
GABRB1 P18505 1/20 0.51
GABRG2 P18507 1/20 0.51
GABRB3 P28472 1/20 0.51
ADORA1 P30542 1/20 0.51
GABRA5 P31644 1/20 0.51
GABRA3 P34903 1/20 0.51
GABRA2 P47869 1/20 0.51
GABRB2 P47870 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8886284 1.00 MEN1 (0.77) MEN1KMT2ALMNAL3MBTL1AURKA
SCHEMBL8883239 0.90 KMT2A (0.63) MEN1KMT2ALMNAL3MBTL1AURKA
SCHEMBL11348908 0.90 LMNA (0.62) MEN1KMT2ALMNAL3MBTL1AURKA
SCHEMBL28738835 0.87 MEN1 (1.00) MEN1KMT2ALMNAL3MBTL1AURKA
SCHEMBL11337561 0.81 TP53 (0.56) MEN1KMT2ALMNAL3MBTL1AURKA
SCHEMBL22103051 0.81 MAT2A (0.72) MEN1KMT2ALMNAL3MBTL1KDM4E
SCHEMBL8885299 0.81 AURKA (0.58) MEN1KMT2ALMNAL3MBTL1AURKA
SCHEMBL18934335 0.81 MEN1 (0.68) MEN1KMT2ALMNAL3MBTL1KDM4E
SCHEMBL4931135 0.81 GABRP (0.56) MEN1KMT2ALMNAL3MBTL1AURKA
SCHEMBL31743740 0.81 MEN1 (0.52) MEN1KMT2ALMNAL3MBTL1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663630-A1 NOVEL BENZIMIDAZOLONE DERIVATIVE COMPOUND AS AUTOTAXIN INHIBITOR LG Chem, Ltd. (KR) 2025-12-17 EP disclosed