Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14404605 | 0.96 | CCR5 (0.69) | CCR5 | |
| SCHEMBL5346505 | 0.91 | CCR5 (0.67) | CCR5 | |
| Hydrochloric Acid SCHEMBL5354767 | 0.91 | CCR5 (0.68) | CCR5 | |
| SCHEMBL14404842 | 0.89 | CCR5 (0.74) | CCR5 | |
| SCHEMBL5344788 | 0.88 | CCR5 (0.73) | CCR5 | |
| Hydrochloric Acid SCHEMBL5343984 | 0.87 | CCR5 (0.74) | CCR5 | |
| SCHEMBL14404722 | 0.86 | CCR5 (0.73) | CCR5 | |
| SCHEMBL14404719 | 0.86 | CCR5 (0.75) | CCR5 | |
| SCHEMBL14404843 | 0.84 | CCR5 (0.65) | CCR5 | |
| SCHEMBL5340771 | 0.84 | CCR5 (0.80) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285552-B2 | Drugs containing triazaspiro[5.5]undecane derivatives as the active ingredient | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-7262193-B2 | Triazaspiro[5.5]undecane derivative and pharmaceutical composition comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |