Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620025 | 1.00 | ALDH1A1 (0.55) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL9160142 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL3729713 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL3729714 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL3029236 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL6158138 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL20808033 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL3029234 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL19480611 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4ECES2CES1LMNA | |
| SCHEMBL24766732 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4ECES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572612-B1 | DIHALO-ALLYLOXY-PHENOL DERIVATIVES HAVING PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2007-10-31 | — | — | EP | disclosed |