Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 14/20 | 0.45 |
| ▸ | KIT | P10721 | 6/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401005 | 0.83 | CSF1R (0.49) | CSF1RKIT | |
| SCHEMBL14404935 | 0.76 | CSF1R (0.49) | CSF1RKITFLT3 | |
| SCHEMBL14405021 | 0.76 | CSF1R (0.51) | CSF1RKIT | |
| SCHEMBL14405017 | 0.75 | CSF1R (0.57) | CSF1RKIT | |
| SCHEMBL14117127 | 0.75 | CSF1R (0.52) | CSF1RKITFLT3 | |
| SCHEMBL3976920 | 0.75 | CSF1R (0.38) | CSF1RKIT | |
| SCHEMBL14404931 | 0.74 | CSF1R (0.71) | CSF1RKIT | |
| SCHEMBL3976921 | 0.74 | CSF1R (0.36) | CSF1RKIT | |
| SCHEMBL14405108 | 0.73 | CSF1R (0.56) | CSF1RKIT | |
| SCHEMBL14405024 | 0.73 | CSF1R (0.56) | CSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249608-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249608-A1 | INHIBITORS OF C-FMS KINASE | MUSK, FRK, FES | CSF1R 59/4885KIT 108/4885FLT3 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.