Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.54 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596750 | 1.00 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL2437322 | 1.00 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12052506 | 1.00 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12296001 | 0.96 | SLC6A4 (0.51) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12295982 | 0.96 | SLC6A4 (0.51) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12296012 | 0.94 | SLC6A4 (0.48) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12052524 | 0.94 | SLC6A4 (0.47) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12327944 | 0.92 | SLC6A4 (0.47) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12328263 | 0.92 | SLC6A4 (0.47) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL439951 | 0.91 | SLC6A4 (0.46) | SLC6A4KCNA5SCN5AKCND2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344162-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2013-01-01 | — | — | US | disclosed |