Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.47 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12295982 | 0.98 | SLC6A4 (0.51) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12296001 | 0.98 | SLC6A4 (0.51) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL14405477 | 0.94 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL2437322 | 0.94 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL18596750 | 0.94 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12052506 | 0.94 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12052524 | 0.87 | SLC6A4 (0.47) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12327944 | 0.86 | SLC6A4 (0.47) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12328263 | 0.86 | SLC6A4 (0.47) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL439953 | 0.85 | SLC6A4 (0.46) | SLC6A4KCNA5SCN5AKCND2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022098-B2 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2011-09-20 | — | — | US | disclosed |
| US-20100152276-A1 | DEUTERATED AMINOCYCLOHEXYL ETHER COMPOUNDS AND PROCESSES FOR PREPARING SAME | CARDIOME PHARMA CORP. (CA) | 2010-06-17 | — | — | US | disclosed |
| US-7705036-B2 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2010-04-27 | — | — | US | disclosed |
| US-20070088075-A1 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088075-A1 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | DDC, HDHD5, DDT | SLC6A4 2668/4885KCNA5 2363/4885SCN5A 4208/4885 |
| US-20100152276-A1 | DEUTERATED AMINOCYCLOHEXYL ETHER COMPOUNDS AND PROCESSES FOR PREPARING SAME | DDC, HDHD5, DDT | SLC6A4 2668/4885KCNA5 2363/4885SCN5A 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.