Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.50 |
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | DDO | Q99489 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468764 | 0.86 | SMYD3 (0.56) | SMYD3KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL34468812 | 0.86 | KDM4E (0.62) | SMYD3KDM4EKMT2ACCR1HSD17B10 | |
| SCHEMBL34468797 | 0.86 | KDM4E (0.62) | SMYD3KDM4EKMT2ACCR1HSD17B10 | |
| SCHEMBL34468866 | 0.86 | KDM4E (0.62) | SMYD3KDM4EKMT2ACCR1HSD17B10 | |
| SCHEMBL34468801 | 0.85 | DRD2 (0.55) | SMYD3KDM4ESMN1; SMN2CCR1TSHR | |
| SCHEMBL34468783 | 0.84 | HPGD (0.58) | SMYD3KDM4ESMN1; SMN2CCR1TSHR | |
| SCHEMBL19414710 | 0.83 | SMYD3 (0.58) | SMYD3KDM4ESMN1; SMN2CCR1TSHR | |
| SCHEMBL34468770 | 0.83 | CCR1 (0.62) | SMYD3KDM4EMEN1KMT2ACCR1 | |
| SCHEMBL34468859 | 0.83 | SMYD3 (0.52) | SMYD3CCR1DAODDO | |
| SCHEMBL34468937 | 0.83 | PADI4 (0.57) | SMYD3KDM4ESMN1; SMN2PADI4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507225-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-10-10 | — | — | EP | claimed |
| WO-2011030349-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-03-17 | — | — | WO | claimed |
| EP-2507225-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011030349-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-03-17 | — | — | WO | disclosed |