Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 8/20 | 0.62 |
| ▸ | SI | P14410 | 6/20 | 0.62 |
| ▸ | AMY2A | P04746 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TREH | O43280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193754 | 0.86 | MGAM (0.73) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL4396739 | 0.86 | MGAM (0.73) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408998 | 0.86 | MGAM (0.73) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14223717 | 0.86 | MGAM (0.73) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408731 | 0.77 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408602 | 0.77 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL5158956 | 0.77 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408606 | 0.77 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408698 | 0.77 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408476 | 0.77 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271158-B2 | Treatment of rumen acidosis with α-amylase inhibitors | PFIZER INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-7271158-B2 | Treatment of rumen acidosis with α-amylase inhibitors | PFIZER INC. (US) | 2007-09-18 | — | — | US | disclosed |