Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 8/20 | 1.00 |
| ▸ | SI | P14410 | 7/20 | 1.00 |
| ▸ | AMY2A | P04746 | 8/20 | 0.68 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408601 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL5159805 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL30937785 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408731 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408476 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL5158956 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408605 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408698 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14408606 | 1.00 | MGAM (1.00) | MGAMSIAMY2AGAAAMY1A | |
| SCHEMBL14416167 | 0.89 | AMY2A (0.87) | MGAMSIAMY2AGAAAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271158-B2 | Treatment of rumen acidosis with α-amylase inhibitors | PFIZER INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-7271158-B2 | Treatment of rumen acidosis with α-amylase inhibitors | PFIZER INC. (US) | 2007-09-18 | — | — | US | disclosed |