Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741777 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1TSHRMEN1HTT | |
| SCHEMBL11735013 | 0.79 | KDM4E (0.37) | KDM4EALDH1A1TSHRMEN1HTT | |
| SCHEMBL1072139 | 0.79 | KDM4E (0.37) | KDM4EALDH1A1TSHRMEN1HTT | |
| SCHEMBL13888339 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1TSHR | |
| SCHEMBL13888354 | 0.75 | KDM4E (0.34) | KDM4EALDH1A1TSHR | |
| SCHEMBL415514 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1TSHRMEN1HTT | |
| SCHEMBL33078 | 0.71 | TSHR (0.39) | KDM4EALDH1A1TSHRMEN1HTT | |
| SCHEMBL1070258 | 0.71 | — | — | |
| SCHEMBL19380536 | 0.71 | TSHR (0.39) | KDM4EALDH1A1TSHRMEN1HTT | |
| SCHEMBL24796703 | 0.71 | KDM4E (0.42) | KDM4EALDH1A1TSHRMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271223-B2 | Norbomene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-09-18 | — | — | US | disclosed |
| US-20070073018-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |