Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 12/20 | 0.74 |
| ▸ | DRD5 | P21918 | 10/20 | 0.74 |
| ▸ | DRD2 | P14416 | 10/20 | 0.71 |
| ▸ | DRD3 | P35462 | 9/20 | 0.71 |
| ▸ | DRD4 | P21917 | 7/20 | 0.71 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21444625 | 0.95 | DRD1 (0.82) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL4323033 | 0.89 | DRD1 (0.72) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29598312 | 0.89 | DRD1 (0.72) | DRD1DRD5DRD2DRD3DRD4 | |
| Bromide SCHEMBL11816300 | 0.84 | DRD1 (0.71) | DRD1DRD5DRD2DRD3DRD4 | |
| Water SCHEMBL11818432 | 0.84 | DRD1 (0.71) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL12158830 | 0.83 | DRD1 (0.76) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL8485819 | 0.82 | DRD1 (0.57) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL10157047 | 0.80 | DRD1 (0.85) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL14409233 | 0.80 | DRD1 (0.56) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL14500169 | 0.79 | DRD1 (0.50) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633715-B1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LTD (GB) | 2007-09-05 | — | — | EP | disclosed |