Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 10/20 | 0.56 |
| ▸ | DRD2 | P14416 | 9/20 | 0.56 |
| ▸ | DRD5 | P21918 | 9/20 | 0.51 |
| ▸ | DRD3 | P35462 | 8/20 | 0.51 |
| ▸ | DRD4 | P21917 | 6/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19650303 | 0.82 | HRH3 (0.49) | HRH3PNMTTMEM97SIGMAR1 | |
| SCHEMBL11474315 | 0.80 | DRD1 (0.82) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL14409246 | 0.80 | DRD1 (0.74) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL7838710 | 0.78 | SLC6A5 (0.53) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL10120338 | 0.76 | HDAC6 (0.57) | — | |
| SCHEMBL21444625 | 0.75 | DRD1 (0.82) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL23395370 | 0.74 | ESR2 (0.49) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL6369552 | 0.73 | PNMT (0.55) | DRD1DRD2DRD3HRH3PRMT5 | |
| SCHEMBL4400467 | 0.72 | CHRM2 (0.61) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL8731853 | 0.72 | HRH3 (0.51) | DRD1DRD2DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633715-B1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LTD (GB) | 2007-09-05 | — | — | EP | disclosed |