Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.64 |
| ▸ | PGR | P06401 | 8/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19236106 | 0.78 | AR (1.00) | ARPGRNR3C2 | |
| SCHEMBL7036414 | 0.75 | AR (0.65) | ARPGRNR3C2 | |
| SCHEMBL7038665 | 0.73 | AR (0.65) | ARPGRNR3C2 | |
| SCHEMBL7036460 | 0.73 | AR (0.65) | ARPGRNR3C2 | |
| SCHEMBL683718 | 0.72 | AR (0.63) | ARPGR | |
| SCHEMBL7037188 | 0.71 | AR (0.63) | ARPGRNR3C2 | |
| SCHEMBL7032596 | 0.70 | AR (0.62) | ARPGRNR3C2 | |
| SCHEMBL2859774 | 0.68 | AR (1.00) | ARPGRNR3C2 | |
| SCHEMBL7037891 | 0.66 | AR (1.00) | ARPGRNR3C2 | |
| SCHEMBL10840954 | 0.64 | AR (0.48) | ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439841-B1 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO INC (US) | 2007-09-19 | — | — | EP | disclosed |
| US-7196076-B2 | Androgen receptor modulators and methods of use thereof | MERCK & CO., INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196076-B2 | Androgen receptor modulators and methods of use thereof | MERCK & CO., INC. (US) | 2007-03-27 | — | — | US | disclosed |