Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.68 |
| ▸ | KDR | P35968 | 9/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14409363 | 0.86 | EPHX2 (0.62) | EPHX2KDR | |
| SCHEMBL14409474 | 0.83 | EPHX2 (0.73) | EPHX2 | |
| SCHEMBL14409357 | 0.83 | EPHX2 (0.58) | EPHX2ABCB1 | |
| SCHEMBL14409364 | 0.81 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL4257145 | 0.80 | EPHX2 (0.71) | EPHX2 | |
| SCHEMBL14409455 | 0.79 | EPHX2 (0.67) | EPHX2 | |
| SCHEMBL4256182 | 0.79 | EPHX2 (0.86) | EPHX2 | |
| SCHEMBL4255865 | 0.79 | EPHX2 (0.76) | EPHX2 | |
| SCHEMBL13701951 | 0.78 | EPHX2 (0.89) | EPHX2 | |
| SCHEMBL4251029 | 0.77 | EPHX2 (0.70) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406892-B1 | PHENYL PYRAZOLE DERIVATIVES AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (US) | 2007-09-05 | — | — | EP | disclosed |