Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | FOS | P01100 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219028 | 1.00 | HRH3 (0.62) | HRH3KCNH2CCR2CCR3PTGS2 | |
| SCHEMBL14409312 | 0.87 | HRH3 (0.75) | HRH3KCNH2PTGS2KMT2AALDH1A1 | |
| SCHEMBL5221321 | 0.87 | HRH3 (0.75) | HRH3KCNH2PTGS2KMT2AALDH1A1 | |
| SCHEMBL14409320 | 0.87 | HRH3 (0.78) | HRH3KCNH2KMT2A | |
| SCHEMBL5223516 | 0.87 | HRH3 (0.78) | HRH3KCNH2KMT2A | |
| SCHEMBL5224172 | 0.86 | HRH3 (0.74) | HRH3KCNH2PTGS2ALDH1A1GAA | |
| SCHEMBL14409347 | 0.86 | HRH3 (0.74) | HRH3KCNH2PTGS2ALDH1A1GAA | |
| SCHEMBL5223528 | 0.85 | HRH3 (0.72) | HRH3KCNH2PTGS2KMT2AALDH1A1 | |
| SCHEMBL14409463 | 0.85 | HRH3 (0.72) | HRH3KCNH2PTGS2KMT2AALDH1A1 | |
| SCHEMBL5217334 | 0.84 | HRH3 (0.66) | HRH3KCNH2CCR2PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474419-B1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK AS (DK) | 2007-09-05 | — | — | EP | disclosed |