Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038490 | 0.93 | ABCB1 (0.55) | ABCB1CNR1CNR2ALDH1A1TP53 | |
| SCHEMBL13648982 | 0.87 | ABCB1 (0.48) | ABCB1CNR1CNR2ALDH1A1TP53 | |
| SCHEMBL13648773 | 0.85 | ABCB1 (0.52) | ABCB1CNR1CNR2ALDH1A1TP53 | |
| SCHEMBL2603350 | 0.84 | CDK5 (0.61) | ABCB1ALDH1A1TP53KDM4EMEN1 | |
| SCHEMBL4034075 | 0.84 | MEN1 (0.60) | ABCB1CNR1CNR2ALDH1A1TP53 | |
| SCHEMBL13648970 | 0.84 | MEN1 (0.60) | ABCB1CNR1CNR2ALDH1A1TP53 | |
| SCHEMBL4043863 | 0.84 | MEN1 (0.60) | ABCB1CNR1CNR2ALDH1A1TP53 | |
| SCHEMBL4043879 | 0.84 | MEN1 (0.60) | ABCB1CNR1CNR2ALDH1A1TP53 | |
| SCHEMBL12639915 | 0.84 | MEN1 (0.60) | ABCB1CNR1CNR2ALDH1A1TP53 | |
| SCHEMBL4044129 | 0.84 | MEN1 (0.60) | ABCB1CNR1CNR2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534698-B1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RES INST (GB) | 2007-09-19 | — | — | EP | disclosed |