Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.61 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.61 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.61 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13648970 | 0.91 | MEN1 (0.60) | CDK5CDK5R1KDM4EMEN1TP53 | |
| SCHEMBL4043863 | 0.91 | MEN1 (0.60) | CDK5CDK5R1KDM4EMEN1TP53 | |
| SCHEMBL582170 | 0.91 | MEN1 (0.60) | CDK5CDK5R1KDM4EMEN1TP53 | |
| SCHEMBL12639915 | 0.91 | MEN1 (0.60) | CDK5CDK5R1KDM4EMEN1TP53 | |
| SCHEMBL4034075 | 0.91 | MEN1 (0.60) | CDK5CDK5R1KDM4EMEN1TP53 | |
| SCHEMBL4043879 | 0.91 | MEN1 (0.60) | CDK5CDK5R1KDM4EMEN1TP53 | |
| SCHEMBL4044129 | 0.91 | MEN1 (0.60) | CDK5CDK5R1KDM4EMEN1TP53 | |
| SCHEMBL4038490 | 0.89 | ABCB1 (0.55) | CDK5CDK5R1KDM4EMEN1TP53 | |
| SCHEMBL29633051 | 0.86 | CYP3A4 (0.60) | KDM4EMEN1TP53CYP3A4MAPT | |
| SCHEMBL4034126 | 0.86 | MEN1 (0.62) | CDK5CDK5R1KDM4EMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188144-B2 | In vitro preservation of living animal cells and compounds suitable for use in the preservation of living animal cells | ANTOXIS LIMITED (GB) | 2012-05-29 | — | — | US | disclosed |
| US-8188144-B2 | In vitro preservation of living animal cells and compounds suitable for use in the preservation of living animal cells | ANTOXIS LIMITED (GB) | 2012-05-29 | — | — | US | disclosed |
| US-20120094384-A1 | USE OF COMPOUNDS FOR DIFFERENTIATION OF CELLS | ANTOXIS LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| US-20120094384-A1 | USE OF COMPOUNDS FOR DIFFERENTIATION OF CELLS | ANTOXIS LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| US-20100267132-A1 | IN VITRO PRESERVATION OF LIVING ANIMAL CELLS AND COMPOUNDS SUITABLE FOR USE IN THE PRESERVATION OF LIVING ANIMAL CELLS | ANTOXIS LIMITED (GB) | 2010-10-21 | — | — | US | disclosed |
| US-20100267132-A1 | IN VITRO PRESERVATION OF LIVING ANIMAL CELLS AND COMPOUNDS SUITABLE FOR USE IN THE PRESERVATION OF LIVING ANIMAL CELLS | ANTOXIS LIMITED (GB) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267132-A1 | IN VITRO PRESERVATION OF LIVING ANIMAL CELLS AND COMPOUNDS SUITABLE FOR USE IN THE PRESERVATION OF LIVING ANIMAL CELLS | PIGS, AQP1, F12 | CDK5 3928/4885CDK5R1 4254/4885KDM4E 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.