Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14411626 | 0.95 | ALDH1A1 (0.44) | ALDH1A1BDKRB1NPC1MEN1KMT2A | |
| SCHEMBL14411622 | 0.90 | BDKRB1 (0.53) | ALDH1A1BDKRB1MEN1KMT2A | |
| SCHEMBL14411578 | 0.89 | BDKRB1 (0.43) | ALDH1A1BDKRB1NPC1MEN1KMT2A | |
| SCHEMBL14411625 | 0.88 | KMT2A (0.42) | ALDH1A1BDKRB1NPC1MEN1KMT2A | |
| SCHEMBL14411698 | 0.87 | BDKRB1 (0.51) | BDKRB1 | |
| SCHEMBL2569876 | 0.86 | BDKRB1 (0.53) | ALDH1A1BDKRB1NPC1MEN1KMT2A | |
| SCHEMBL14411628 | 0.85 | BDKRB1 (0.49) | BDKRB1CASP3CASP7 | |
| SCHEMBL14411516 | 0.84 | BDKRB1 (0.45) | BDKRB1NPC1MEN1KMT2AMAPK1 | |
| SCHEMBL2572140 | 0.83 | EBP (0.53) | BDKRB1NPC1MEN1KMT2AEBP | |
| SCHEMBL14411691 | 0.83 | BDKRB1 (0.50) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007101007-A2 | ARYL SULFONYL HETEROCYCLES | NEUROGEN CORPORATION (US) | 2007-09-07 | — | — | WO | disclosed |