Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594964 | 0.87 | ALDH1A1 (0.56) | ALDH1A1GAAL3MBTL1POLBPROKR1 | |
| SCHEMBL1594796 | 0.87 | ALDH1A1 (0.56) | ALDH1A1GAAL3MBTL1POLBPROKR1 | |
| SCHEMBL1594152 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAAL3MBTL1POLBPROKR1 | |
| SCHEMBL1594746 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAAL3MBTL1POLBPROKR1 | |
| SCHEMBL1594606 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAAL3MBTL1POLBPROKR1 | |
| SCHEMBL1594150 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAAL3MBTL1POLBPROKR1 | |
| SCHEMBL1594124 | 0.85 | ALDH1A1 (0.53) | ALDH1A1GAAL3MBTL1POLBRAB9A | |
| SCHEMBL1593690 | 0.85 | ALDH1A1 (0.65) | ALDH1A1GAAL3MBTL1POLBKDM4E | |
| SCHEMBL1594515 | 0.85 | ALDH1A1 (0.65) | ALDH1A1GAAL3MBTL1POLBKDM4E | |
| SCHEMBL1593277 | 0.84 | ALDH1A1 (0.59) | ALDH1A1GAAL3MBTL1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007100851-A1 | THERAPEUTIC COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |