Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 7/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31381205 | 0.84 | SCD (0.61) | EPHX2SCDRBP4 | |
| SCHEMBL2764082 | 0.83 | CYP2C9 (0.47) | EPHX2CYP2C9CYP2J2HSD11B1SCD | |
| SCHEMBL14413529 | 0.83 | EPHX2 (0.59) | EPHX2PIM1PIM2 | |
| SCHEMBL4096764 | 0.82 | KDM1A (0.54) | EPHX2CYP2C9CYP2J2 | |
| SCHEMBL13873160 | 0.81 | EPHX2 (0.56) | EPHX2CYP2C9CYP2J2SCN9ARBP4 | |
| SCHEMBL14413611 | 0.80 | PIM1 (0.47) | EPHX2SCDPIM1PIM2RBP4 | |
| SCHEMBL3111770 | 0.78 | RBP4 (0.65) | EPHX2SCDPIM1PIM2RBP4 | |
| SCHEMBL3339119 | 0.78 | EPHX2 (0.47) | EPHX2CYP2C9CYP2J2HSD11B1SCD | |
| SCHEMBL14412821 | 0.75 | EPHX2 (0.57) | EPHX2CYP2C9CYP2J2 | |
| SCHEMBL646216 | 0.75 | EPHX2 (0.41) | EPHX2CYP2C9CYP2J2PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |