Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.68 |
| ▸ | PPARD | Q03181 | 14/20 | 0.68 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530905 | 0.88 | FFAR1 (0.73) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14378490 | 0.85 | FFAR1 (0.64) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14378539 | 0.76 | FFAR1 (0.61) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14378541 | 0.76 | FFAR1 (0.61) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL4788448 | 0.76 | FFAR1 (0.61) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14402406 | 0.76 | PPARD (0.60) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14412915 | 0.74 | PPARD (0.59) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14402122 | 0.74 | FFAR1 (0.42) | FFAR1PPARDPPARG | |
| SCHEMBL14402254 | 0.73 | PPARD (0.56) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14378597 | 0.73 | PPARA (0.71) | FFAR1PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106469-A2 | BICYCLIC CARBOXYLIC ACID DERIVATIVES USEFUL FOR TREATING METABOLIC DISORDERS | AMGEN INC. (US) | 2007-09-20 | — | — | WO | disclosed |