Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.64 |
| ▸ | PPARD | Q03181 | 14/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530905 | 0.92 | FFAR1 (0.73) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14412903 | 0.85 | FFAR1 (0.68) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL5525113 | 0.79 | PPARD (0.55) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14378497 | 0.73 | FFAR1 (0.46) | FFAR1PPARDPPARG | |
| SCHEMBL4815564 | 0.71 | PPARD (0.64) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14378597 | 0.70 | PPARA (0.71) | FFAR1PPARDPPARGPPARA | |
| SCHEMBL14378611 | 0.70 | FFAR1 (0.66) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14378541 | 0.70 | FFAR1 (0.61) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL14378539 | 0.70 | FFAR1 (0.61) | FFAR1PPARDPPARGPPARACYP2C9 | |
| SCHEMBL4788448 | 0.70 | FFAR1 (0.61) | FFAR1PPARDPPARGPPARACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244155-A1 | Bicyclic carboxylic acid derivatives useful for treating metabolic disorders | AMGEN INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244155-A1 | Bicyclic carboxylic acid derivatives useful for treating metabolic disorders | AMGEN INC. (US) | 2007-10-18 | — | — | US | disclosed |
| WO-2007106469-A2 | BICYCLIC CARBOXYLIC ACID DERIVATIVES USEFUL FOR TREATING METABOLIC DISORDERS | AMGEN INC. (US) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244155-A1 | Bicyclic carboxylic acid derivatives useful for treating metabolic disorders | GOT2, PC, GOT1 | FFAR1 326/4885PPARD 243/4885PPARG 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.