Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413282 | 0.99 | HSD11B1 (0.44) | HSD11B1 | |
| SCHEMBL12809592 | 0.99 | HSD11B1 (0.44) | HSD11B1 | |
| SCHEMBL12809467 | 0.87 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL14413260 | 0.87 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL12809716 | 0.86 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL14412839 | 0.86 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL13294030 | 0.85 | HSD11B1 (0.59) | HSD11B1 | |
| SCHEMBL14413258 | 0.84 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL12809586 | 0.83 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL14413277 | 0.83 | HSD11B1 (0.37) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007107470-A2 | PYRAZOLES AS 11-BETA-HSD-1 | F. HOFFMANN-LA ROCHE AG (CH) | 2007-09-27 | — | — | WO | disclosed |