Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413752 | 0.89 | ADORA1 (0.54) | ADORA1ADORA2AADORA2BMAPTRXFP1 | |
| SCHEMBL14413003 | 0.79 | RIPK2 (0.48) | MAPTHPGDPOLBDHFRHSD17B10 | |
| SCHEMBL4905916 | 0.79 | ADORA1 (0.77) | ADORA1ADORA2AADORA2BMAPTRXFP1 | |
| SCHEMBL4898198 | 0.78 | HPGD (0.41) | ADORA1ADORA2AMAPTHPGDALDH1A1 | |
| SCHEMBL5321086 | 0.78 | ADORA1 (0.70) | ADORA1ADORA2AADORA2BMAPTHPGD | |
| SCHEMBL5326783 | 0.77 | ADORA1 (0.52) | ADORA1ADORA2AADORA2BMAPTRXFP1 | |
| SCHEMBL14413001 | 0.75 | ADORA1 (0.58) | ADORA1ADORA2AADORA2BRXFP1HPGD | |
| SCHEMBL14413781 | 0.75 | ADORA1 (0.52) | ADORA1ADORA2AADORA2BHPGDALDH1A1 | |
| SCHEMBL4911968 | 0.73 | ADORA1 (0.53) | ADORA1ADORA2AADORA2BMAPTRXFP1 | |
| SCHEMBL2569855 | 0.72 | ADORA1 (0.77) | ADORA1ADORA2AADORA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098835-A1 | AMINO PYRYMIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-09-07 | — | — | WO | disclosed |