Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15895045 | 0.95 | TSHR (0.39) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL16638481 | 0.90 | USP2 (0.46) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL15895136 | 0.90 | TSHR (0.35) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL17792592 | 0.88 | TSHR (0.44) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL18611903 | 0.88 | LPAR6 (0.36) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL16358125 | 0.88 | USP2 (0.39) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL6229989 | 0.85 | TSHR (0.41) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL7540913 | 0.82 | MGAM (0.36) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL6036788 | 0.82 | TSHR (0.50) | TSHRALDH1A1CNR2CNR1MGAM | |
| SCHEMBL14400398 | 0.82 | USP2 (0.46) | TSHRMGAMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |
| WO-2007098597-A1 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2007-09-07 | — | — | WO | disclosed |