Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358125 | 0.91 | USP2 (0.39) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL14413619 | 0.90 | TSHR (0.39) | USP2TSHRMGAMALDH1A1CNR1 | |
| SCHEMBL16627345 | 0.89 | USP2 (0.48) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL14747623 | 0.88 | USP2 (0.46) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL14400396 | 0.88 | USP2 (0.46) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL12960564 | 0.88 | USP2 (0.46) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL12671784 | 0.88 | USP2 (0.46) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL14400398 | 0.88 | USP2 (0.46) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL14747646 | 0.88 | USP2 (0.46) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL14413833 | 0.88 | USP2 (0.46) | USP2TSHRLPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9005578-B2 | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders | FLUOROPHARMA, INC. (US) | 2015-04-14 | — | — | US | disclosed |