Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.45 |
| ▸ | GBA1 | P04062 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14605407 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL15505953 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL13074853 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL15871863 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL280129 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL15505946 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL17736037 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL16731206 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL14413551 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 | |
| SCHEMBL13222913 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2SMPD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |
| WO-2007098597-A1 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2007-09-07 | — | — | WO | disclosed |