Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830964 | 0.86 | MAPK1 (0.36) | MAPK1ATMCHRM1MEN1USP2 | |
| SCHEMBL11735795 | 0.82 | MAPK1 (0.32) | MAPK1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL9953612 | 0.79 | MAPK1 (0.34) | MAPK1ATMCHRM1MEN1USP2 | |
| SCHEMBL5045818 | 0.79 | MAPK1 (0.34) | MAPK1ATMALDH1A1LMNATHRB | |
| SCHEMBL11832305 | 0.75 | MAPK1 (0.31) | MAPK1ATM | |
| SCHEMBL11831691 | 0.75 | MAPK1 (0.31) | MAPK1ATM | |
| SCHEMBL11830920 | 0.75 | MAPK1 (0.31) | MAPK1ATM | |
| SCHEMBL11750132 | 0.75 | CHRM1 (0.35) | MAPK1ATMCHRM1ALDH1A1 | |
| SCHEMBL9710856 | 0.75 | MEN1 (0.31) | MEN1USP2POLBKMT2A | |
| SCHEMBL1187005 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700574-B2 | Use of secnidazole in treatment of dental infections | ATHENA PHARMACEUTIQUES SAS (FR) | 2017-07-11 | — | — | US | disclosed |
| EP-2709617-B1 | SECNIDAZOLE FOR USE IN COMBINATION IN THE ORAL TREATMENT OF DENTAL INFECTIONS | VEGEFARM (FR) | 2015-11-25 | — | — | EP | disclosed |
| EP-2709617-A1 | THE USE OF SECNIDAZOLE IN TREATING DENTAL INFECTIONS | Madeca (FR) | 2014-03-26 | — | — | EP | disclosed |
| US-20140080778-A1 | USE OF SECNIDAZOLE IN TREATMENT OF DENTAL INFECTIONS | MADECA (FR) | 2014-03-20 | — | — | US | disclosed |
| WO-2012156599-A1 | THE USE OF SECNIDAZOLE IN TREATING DENTAL INFECTIONS | MADECA (FR) | 2012-11-22 | — | — | WO | disclosed |
| WO-2011027046-A1 | USE OF SECNIDAZOLE IN COMBINATION WITH AN ACTIVE ANTIBIOTIC AGAINST AEROBIC BACTERIA FOR TREATING DIVERTICULITIS | MADECA (FR) | 2011-03-10 | — | — | WO | disclosed |