Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830964 | 0.78 | MAPK1 (0.36) | MEN1USP2POLBKMT2A | |
| SCHEMBL1441383 | 0.75 | MAPK1 (0.38) | MEN1USP2POLBKMT2A | |
| SCHEMBL9953612 | 0.74 | MAPK1 (0.34) | MEN1USP2POLBKMT2A | |
| SCHEMBL11735795 | 0.74 | MAPK1 (0.32) | MEN1KMT2A | |
| SCHEMBL11791613 | 0.74 | CYP2C19 (0.32) | — | |
| SCHEMBL11779971 | 0.73 | — | — | |
| SCHEMBL5045818 | 0.71 | MAPK1 (0.34) | — | |
| SCHEMBL4411442 | 0.70 | CYP2C19 (0.33) | — | |
| SCHEMBL11617678 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL8803303 | 0.68 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324692-B1 | PROCESS FOR THE PREPARATION OF HYDROXYALKYLATING AGENTS, THE AGENTS AS PREPARED AND THEIR USE | RHONE-POULENC SANTE (FR) | 1992-11-25 | — | — | EP | claimed |
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | claimed |
| CN-1035111-A | Hydroxyalkyl agent preparation method, gained new preparation and application thereof like this | RHONE POULENC SANTE (FR) | 1989-08-30 | — | — | CN | claimed |
| JP-1216976-A | — | — | None | — | — | JP | disclosed |
| CN-1023318-C | Process for preparing 1-hydroxyalkyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1993-12-29 | — | — | CN | disclosed |
| CN-1023220-C | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1993-12-22 | — | — | CN | disclosed |
| CN-1055536-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC RORER SA (FR) | 1991-10-23 | — | — | CN | disclosed |
| CN-1055536-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC RORER SA (FR) | 1991-10-23 | — | — | CN | disclosed |
| CN-1055536-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC RORER SA (FR) | 1991-10-23 | — | — | CN | disclosed |
| US-5023361-A | Process for preparing hydroxyalkylating agents, the agents so obtained, and their use | RHONE-POULENC SANTE (FR) | 1991-06-11 | — | — | US | disclosed |
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925951-A | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925952-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925952-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| CN-1035288-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| CN-1035288-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| CN-1035289-A | The preparation method of 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| JP-H01216976-A | PREPARATION OF 1-HYDROXYALKYL-5-NITROIMIDAZOLE | RHONE POULENC SANTE | 1989-08-30 | — | — | JP | disclosed |
| EP-0324691-A1 | Process for the preparation of 1-hydroxyalkyl-5-nitro-imidazoles | RHONE-POULENC SANTE (FR) | 1989-07-19 | — | — | EP | disclosed |