Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.44 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.44 |
| ▸ | GJB2 | P29033 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747620 | 0.95 | MAPK1 (0.52) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL28276208 | 0.91 | MAPK1 (0.56) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL28274960 | 0.91 | MAPK1 (0.56) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL21080958 | 0.91 | MAPK1 (0.44) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL16421742 | 0.91 | TNF (0.56) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL17304977 | 0.91 | TNF (0.56) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL13885908 | 0.91 | TNF (0.56) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL15499729 | 0.91 | TNF (0.56) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL5678760 | 0.90 | MAPK1 (0.58) | MAPK1GBA1TNFSLC2A1LGALS8 | |
| SCHEMBL25415166 | 0.89 | MAPK1 (0.60) | MAPK1GBA1TNFSLC2A1LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |
| WO-2007098597-A1 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2007-09-07 | — | — | WO | disclosed |