SCHEMBL5678760

SCHEMBL5678760

CCCCCOC1O[C@H](CO)[C@@H](O)[C@H]1OCCCCC

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.58
▸ GBA1 P04062 3/20 0.51
▸ SLC2A1 P11166 1/20 0.48
▸ LGALS8 O00214 1/20 0.47
▸ LGALS3 P17931 1/20 0.47
▸ LGALS4 P56470 1/20 0.47
▸ GJB2 P29033 1/20 0.46
▸ TNF P01375 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25415166 0.98 MAPK1 (0.60) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL25415432 0.98 MAPK1 (0.60) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL25414516 0.98 MAPK1 (0.60) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL546864 0.95 MAPK1 (0.60) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL14747620 0.95 MAPK1 (0.52) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL25417760 0.92 MAPK1 (0.54) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL28276208 0.91 MAPK1 (0.56) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL28274960 0.91 MAPK1 (0.56) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL8370478 0.91 MAPK1 (0.60) MAPK1GBA1SLC2A1LGALS8LGALS3
SCHEMBL8370481 0.91 MAPK1 (0.60) MAPK1GBA1SLC2A1LGALS8LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1747961-A Process for producing ribofuranose derivative INALCO SPA (IT) 2006-03-15 — — CN disclosed
EP-1631573-A1 PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES INALCO SpA (IT) 2006-03-08 — — EP disclosed
US-6891036-B2 Process for the preparation of ribofuranose derivatives INALCO S.P.A. (IT) 2005-05-10 — — US disclosed
WO-2004069851-A1 PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES INALCO S.P.A. (IT) 2004-08-19 — — WO disclosed
US-20040158059-A1 Process for the preparation of ribofuranose derivatives INALCO S.P.A. (IT) 2004-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158059-A1 Process for the preparation of ribofuranose derivatives RNGTT, RPIA, MRM1 MAPK1 2206/4885GBA1 1204/4885SLC2A1 1004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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