SCHEMBL144145

SCHEMBL144145

CCOC(=O)CN(C(=O)CCl)c1c(CC)cccc1CC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.65
ALDH1A1 P00352 6/20 0.59
TDP1 Q9NUW8 2/20 0.59
NR1I2 O75469 1/20 0.59
CYP3A4 P08684 1/20 0.59
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
NLRP3 Q96P20 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
PAX8 Q06710 3/20 0.39
GPX4 P36969 1/20 0.39
JAK2 O60674 2/20 0.38
HTT P42858 1/20 0.38
THRB P10828 1/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pretilachlor SCHEMBL11164073 0.88 NR1I2 (0.82) TP53ALDH1A1TDP1NR1I2CYP3A4
SCHEMBL11131439 0.88 TDP1 (0.69) TP53ALDH1A1TDP1NR1I2CYP3A4
SCHEMBL11135503 0.87 TP53 (0.56) TP53ALDH1A1TDP1NR1I2CYP3A4
SCHEMBL9205663 0.87 ALDH1A1 (0.57) TP53ALDH1A1TDP1NR1I2CYP3A4
SCHEMBL9781353 0.86 NR1I2 (0.64) TP53ALDH1A1TDP1NR1I2CYP3A4
SCHEMBL11143799 0.86 TDP1 (0.62) TP53ALDH1A1TDP1NR1I2CYP3A4
SCHEMBL11760442 0.85 TP53 (0.47) TP53ALDH1A1TDP1NR1I2CYP3A4
SCHEMBL11167093 0.85 TP53 (0.60) TP53ALDH1A1TDP1NR1I2CYP3A4
Endothall SCHEMBL9819183 0.84 TP53 (0.48) TP53ALDH1A1TDP1NR1I2CYP3A4
SCHEMBL131683 0.83 TP53 (0.66) TP53ALDH1A1TDP1NR1I2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2522 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
CN-117169390-B Method for determining antoin in blood, kit and application 宁波市疾病预防控制中心(宁波市健康教育与促进中心) 2024-05-03 CN claimed
US-20240130368-A1 HERBICIDAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2024-04-25 US claimed
EP-3837573-B1 MEMS/NEMS INTEGRATED BROKEN RACETRACK TUNABLE LASER DIODE ERICSSON TELEFON AB L M (SE) 2024-03-06 EP claimed
EP-4316244-A1 HERBICIDAL COMPOSITION Nippon Soda Co., Ltd. (JP) 2024-02-07 EP claimed
WO-2024009297-A1 STABLE OIL DISPERSIONS ADAMA AGAN LTD. (IL) 2024-01-11 WO claimed
CN-117169390-A Method for determining antoin in blood, kit and application 宁波市疾病预防控制中心(宁波市健康教育与促进中心) 2023-12-05 CN claimed
CN-219338845-U Reflective bubble aluminum heat-insulating film blanket for reducing loss, energy and carbon of grain and grain oil 圆创享(苏州)新材料技术有限公司 2023-07-14 CN claimed
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2023-01-05 US claimed
US-11518604-B2 Systems, methods and devices for aerosol spraying of silicone based topical skin adhesives for sealing wounds ETHICON, INC. (US) 2022-12-06 US claimed
US-5424324-A Stabilized microbiocides ROHM AND HAAS COMPANY (US) 1995-06-13 US claimed
CN-1024488-C Benzhydryl compounds as henbicide antidotes MONSANTO CO (US) 1994-05-18 CN claimed
WO-1993005653-A1 SYNERGISTIC HERBICIDAL COMPOSITIONS SCHERING AKTIENGESELLSCHAFT (DE) 1993-04-01 WO claimed
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
US-5108482-A Protect crep plant against phytotoxic action of herbicide; plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-04-28 US claimed
EP-0435439-A2 Aldehyde stabilizers for 3-isothiazolones ROHM AND HAAS COMPANY (US) 1991-07-03 EP claimed
EP-0397602-A1 N-phenylpyrrolidines CIBA-GEIGY AG (CH) 1990-11-14 EP claimed
EP-0357557-A2 Synergistic mixture CIBA-GEIGY AG (CH) 1990-03-07 EP claimed
US-4284427-A Herbicidal composition for paddy fields KANESHO COMPANY LIMITED (JP) 1981-08-18 US claimed
US-4256481-A Selective herbicide compositions NITROKEMIA IPARTELEPEK (HU) 1981-03-17 US claimed