Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD69 | Q07108 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.45 |
| ▸ | PYGB | P11216 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936528 | 1.00 | CD69 (0.48) | CD69MAPK1LGALS8PYGBPTPN1 | |
| SCHEMBL2429109 | 0.95 | CD69 (0.53) | CD69MAPK1LGALS8PYGBPRKCA | |
| SCHEMBL16260821 | 0.95 | CD69 (0.47) | CD69MAPK1LGALS8PYGBPTPN1 | |
| SCHEMBL15679585 | 0.95 | CD69 (0.47) | CD69MAPK1LGALS8PYGBPTPN1 | |
| SCHEMBL16683389 | 0.95 | CD69 (0.53) | CD69MAPK1LGALS8PYGBPRKCA | |
| SCHEMBL8361872 | 0.95 | CD69 (0.53) | CD69MAPK1LGALS8PYGBPRKCA | |
| SCHEMBL8772683 | 0.95 | CD69 (0.47) | CD69MAPK1LGALS8PYGBPTPN1 | |
| SCHEMBL6268182 | 0.95 | CD69 (0.53) | CD69MAPK1LGALS8PYGBPRKCA | |
| SCHEMBL10022858 | 0.95 | CD69 (0.47) | CD69MAPK1LGALS8PYGBPTPN1 | |
| SCHEMBL7515919 | 0.95 | CD69 (0.53) | CD69MAPK1LGALS8PYGBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225246-A1 | O-acetyl-ADP-ribose non-hydrolyzable analogs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225246-A1 | O-acetyl-ADP-ribose non-hydrolyzable analogs | PARP1, TIPARP, CD38 | CD69 3225/4885MAPK1 3912/4885LGALS8 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.