Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD69 | Q07108 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PYGB | P11216 | 2/20 | 0.42 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16683389 | 1.00 | CD69 (0.53) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL2429109 | 1.00 | CD69 (0.53) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL8021265 | 1.00 | CD69 (0.53) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL7515919 | 1.00 | CD69 (0.53) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL8166277 | 1.00 | CD69 (0.53) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL8361872 | 1.00 | CD69 (0.53) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL14414822 | 0.95 | CD69 (0.48) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL6936528 | 0.95 | CD69 (0.48) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL10022858 | 0.89 | CD69 (0.47) | CD69MAPK1PYGBLGALS8KDM4E | |
| SCHEMBL16260821 | 0.89 | CD69 (0.47) | CD69MAPK1PYGBLGALS8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2850084-A1 | PYRAZOLE COMPOUNDS AS SGLT1 INHIBITORS | Eli Lilly and Company (US) | 2015-03-25 | — | — | EP | disclosed |
| WO-2013169546-A1 | PYRAZOLE COMPOUNDS AS SGLT1 INHIBITORS | ELI LILLY AND COMPANY (US) | 2013-11-14 | — | — | WO | disclosed |
| EP-1270584-B1 | GLUCOPYRANOSYLOXY BENZYLBENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES FOR THE PREPARATION OF THE DERIVATIVES | KISSEI PHARMACEUTICAL (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-1329456-A1 | GLUCOPYRANOSYLOXYBENZYLBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-1270584-A1 | GLUCOPYRANOSYLOXY BENZYLBENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES FOR THE PREPARATION OF THE DERIVATIVES | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-0816375-A1 | GLYCOCONJUGATES OF OPIATED SUBSTANCES | ROLABO SL (ES) | 1998-01-07 | — | — | EP | disclosed |
| WO-1993024505-A1 | REDUCING INFLAMMATION BY TIME DEPENDENT ADMINISTRATION OF OLIGOSACCHARIDES GLYCOSIDES RELATED TO BLOOD GROUP DETERMINANTS | ALBERTA RESEARCH COUNCIL (CA) | 1993-12-09 | — | — | WO | disclosed |
| EP-0549665-A1 | POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992005444-A1 | POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-02 | — | — | WO | disclosed |