Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.62 |
| ▸ | FBP1 | P09467 | 1/20 | 0.56 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | IGF2R | P11717 | 4/20 | 0.42 |
| ▸ | PGD | P52209 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.37 |
| ▸ | UMPS | P11172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14414838 | 1.00 | AMDHD2 (0.62) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL29394667 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL4363206 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL29425232 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL20558753 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL25361382 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL14669223 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL4363197 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL20912983 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 | |
| SCHEMBL20299968 | 0.96 | AMDHD2 (0.68) | AMDHD2FBP1LGALS3MAPK1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225246-A1 | O-acetyl-ADP-ribose non-hydrolyzable analogs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225246-A1 | O-acetyl-ADP-ribose non-hydrolyzable analogs | PARP1, TIPARP, CD38 | AMDHD2 21/4885FBP1 687/4885LGALS3 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.