Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.68 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | IGF2R | P11717 | 4/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | HK2 | P52789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394667 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL20291477 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL4363197 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL29425232 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL20299968 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL25361382 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL14669223 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL20912983 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL20558753 | 1.00 | AMDHD2 (0.68) | AMDHD2FBP1MAPK1IGF2RLGALS3 | |
| SCHEMBL14414838 | 0.96 | AMDHD2 (0.62) | AMDHD2FBP1MAPK1IGF2RLGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186358-A1 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof | WYETH (US) | 2009-07-23 | — | — | US | disclosed |