Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Delucemine SCHEMBL678708 | 0.87 | HTR2A (0.63) | SLC6A4HTR2AHRH1SLC6A2SLC6A3 | |
| Delucemine SCHEMBL1661363 | 0.85 | HTR2A (0.61) | SLC6A4HTR2AHRH1SLC6A2SLC6A3 | |
| Delucemine SCHEMBL1649904 | 0.84 | HTR2A (0.59) | SLC6A4HTR2AHRH1SLC6A2SLC6A3 | |
| SCHEMBL6900402 | 0.84 | HTR2A (0.70) | SLC6A4HTR2AHRH1SLC6A2SLC6A3 | |
| SCHEMBL14415665 | 0.83 | HRH1 (0.46) | SLC6A4HRH1SLC6A2SHBGTAAR1 | |
| SCHEMBL14415663 | 0.82 | SLC6A4 (0.50) | SLC6A4HTR2AHRH1SLC6A2SLC6A3 | |
| SCHEMBL14415637 | 0.77 | SLC6A4 (0.60) | SLC6A4HTR2AHRH1SLC6A2 | |
| SCHEMBL2299572 | 0.75 | SHBG (0.55) | SHBG | |
| SCHEMBL2305030 | 0.75 | SLC6A4 (0.55) | SLC6A4HTR2AHRH1SLC6A2SLC6A3 | |
| SCHEMBL6050357 | 0.75 | SLC6A4 (0.54) | SLC6A4HTR2AHRH1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268166-B2 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases | NPS PHARMACEUTICALS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268166-B2 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases | NPS PHARMACEUTICALS, INC. (US) | 2007-09-11 | — | — | US | disclosed |