Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047415 | 0.93 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL5048818 | 0.88 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL5043375 | 0.88 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL5047495 | 0.86 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL14415779 | 0.83 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL14415774 | 0.82 | PTPN11 (0.31) | — | |
| SCHEMBL5045685 | 0.80 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL5048460 | 0.77 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL5518409 | 0.76 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL14415776 | 0.73 | CRHR1 (0.43) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268146-B2 | Ring fused pyrazole derivatives as CRF antagonists | PALO ALTO LLC (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268146-B2 | Ring fused pyrazole derivatives as CRF antagonists | PALO ALTO LLC (US) | 2007-09-11 | — | — | US | disclosed |