Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993166 | 0.86 | CETP (1.00) | CETPP2RX7 | |
| SCHEMBL13212564 | 0.83 | CETP (0.79) | CETPP2RX7 | |
| SCHEMBL12841393 | 0.82 | CETP (0.77) | CETPP2RX7 | |
| SCHEMBL23976840 | 0.82 | CETP (0.77) | CETPP2RX7 | |
| SCHEMBL23977331 | 0.81 | CETP (0.74) | CETP | |
| SCHEMBL1525537 | 0.79 | CETP (1.00) | CETPP2RX7 | |
| SCHEMBL13212357 | 0.79 | CETP (0.71) | CETPP2RX7 | |
| SCHEMBL1524190 | 0.78 | CETP (0.70) | CETPP2RX7 | |
| SCHEMBL13212434 | 0.77 | CETP (0.69) | CETPP2RX7 | |
| SCHEMBL1524902 | 0.77 | P2RX7 (0.73) | CETPP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000045-B2 | CETP activity inhibitors | JAPAN TOBACCO INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20130053417-A1 | CETP ACTIVITY INHIBITORS | JAPAN TOBACCO INC. (JP) | 2013-02-28 | — | — | US | disclosed |
| US-7271196-B2 | cholesterol ester transfer protein inhibitors, new type of a preventive or therapeutic agent for atherosclerosis or hyperlipidemia | JAPAN TABACCO INC. (JP) | 2007-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053417-A1 | CETP ACTIVITY INHIBITORS | CETP, PCSK9, LCAT | CETP 1/4885P2RX7 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.