Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.50 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420638 | 0.90 | CCR5 (0.54) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL14416482 | 0.89 | CCR5 (0.52) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL3881134 | 0.82 | CCR5 (0.57) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL3881140 | 0.82 | CCR5 (0.57) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL14416483 | 0.81 | CCR5 (0.53) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL14416418 | 0.81 | CCR5 (0.53) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL15246903 | 0.81 | CCR5 (0.56) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL4130344 | 0.81 | CCR5 (0.54) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL14420637 | 0.81 | CCR5 (0.54) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL14416480 | 0.81 | CCR5 (0.56) | CCR5KCNH2CYP3A4ADRA2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070218486-A1 | Immunoassays, Haptens, Immunogens and Antibodies for Anti-HIV Therapeutics | ARK DIAGNOSTICS, INC. (US) | 2007-09-20 | — | — | US | disclosed |