Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 3/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | RPA1 | P27694 | 6/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14416559 | 0.89 | CNR1 (0.47) | MARS1CACNA1GCACNA1HCNR1CNR2 | |
| SCHEMBL5523089 | 0.86 | CNR1 (0.53) | MARS1CACNA1GCACNA1HCNR1CNR2 | |
| SCHEMBL5526243 | 0.85 | CNR1 (0.49) | MARS1CACNA1GCACNA1HCNR1CNR2 | |
| SCHEMBL5522940 | 0.82 | NAMPT (0.47) | MARS1CACNA1GCACNA1HCNR1CNR2 | |
| SCHEMBL5529778 | 0.81 | CNR1 (0.52) | MARS1CACNA1GCACNA1HCNR1CNR2 | |
| SCHEMBL5529584 | 0.80 | CNR1 (0.49) | MARS1CNR1CNR2RPA1DHODH | |
| SCHEMBL5531835 | 0.80 | CNR1 (0.51) | MARS1CACNA1GCACNA1HCNR1CNR2 | |
| SCHEMBL5526417 | 0.79 | CNR1 (0.48) | MARS1CACNA1GCACNA1HCNR1CNR2 | |
| SCHEMBL5525413 | 0.79 | CNR1 (0.48) | MARS1CACNA1GCACNA1HCNR1CNR2 | |
| SCHEMBL5526193 | 0.77 | CNR1 (0.50) | MARS1CACNA1GCACNA1HCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | MARS1 2982/4885CACNA1G 3126/4885CACNA1H 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.