Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112890 | 1.00 | PLK1 (0.50) | PLK1TP53TRPV1SLC6A5KDM1A | |
| SCHEMBL31206178 | 0.86 | EPHX1 (0.50) | TP53KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL31205972 | 0.82 | EPHX1 (0.55) | KDM1AMAOBEPHX1EPHX2DRD2 | |
| SCHEMBL12864600 | 0.82 | PLK1 (0.57) | PLK1TP53TRPV1TSHRKMT2A | |
| SCHEMBL10112894 | 0.81 | SMYD3 (0.57) | PLK1TP53TRPV1 | |
| SCHEMBL10133700 | 0.81 | SMYD3 (0.57) | PLK1TP53TRPV1 | |
| SCHEMBL25398746 | 0.80 | HDAC4 (0.53) | TP53SLC6A5TSHRKMT2AL3MBTL1 | |
| SCHEMBL8341550 | 0.80 | NAMPT (0.55) | KMT2AL3MBTL1EPHX1 | |
| SCHEMBL10113046 | 0.80 | PLK1 (0.49) | PLK1TP53TRPV1SLC6A5TSHR | |
| SCHEMBL10133291 | 0.80 | PLK1 (0.49) | PLK1TP53TRPV1SLC6A5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |