Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 6/20 | 0.43 |
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206178 | 0.96 | EPHX1 (0.50) | EPHX1EPHX2KDM1AMAOBDRD2 | |
| SCHEMBL25042210 | 0.89 | EPHX1 (0.42) | EPHX1EPHX2KDM1AMAOBDRD2 | |
| SCHEMBL31205868 | 0.89 | EPHX1 (0.42) | EPHX1EPHX2KDM1AMAOBDRD2 | |
| SCHEMBL31206194 | 0.85 | CNR1 (0.49) | CNR1CNR2KDM1AMAOBDRD2 | |
| SCHEMBL26554480 | 0.84 | NAMPT (0.56) | EPHX1EPHX2SPHK1CNR2 | |
| SCHEMBL31206125 | 0.83 | CNR2 (0.41) | EPHX1EPHX2CNR1CNR2KDM1A | |
| SCHEMBL25041556 | 0.83 | CNR2 (0.41) | EPHX1EPHX2CNR1CNR2KDM1A | |
| SCHEMBL14418239 | 0.82 | PLK1 (0.50) | EPHX1EPHX2SPHK1KDM1AMAOB | |
| SCHEMBL10112890 | 0.82 | PLK1 (0.50) | EPHX1EPHX2SPHK1KDM1AMAOB | |
| SCHEMBL31206094 | 0.81 | DRD2 (0.48) | EPHX2KDM1AMAOBDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | AIFM2, GPX1, GPX4 | EPHX1 1233/4885EPHX2 1958/4885SPHK1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.